Gerard P . Sergeant Eamonn Bradley , Mark A . Hollywood , Noel G . McHale , Keith D . Thornbury and dependent on capacitative calcium entry Pacemaker activity in urethral interstitial cells is not
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[PDF] [Full Text] [Abstract] , November 1, 2006; 576 (3): 715-720. J Physiol Gerard P. Sergeant, M. A. Hollywood, N. G. McHale and K. D. Thornbury signalling in urethral interstitial cells of Cajal 2+ Ca [PDF] , January 5, 2007; . Mol. Hum. Reprod. A. Dalrymple, K. Mahn, L. Poston, E. Songu-Mize and R.M. Tribe smooth muscle cells Mechanical stretch regulates TRPC expression and calcium entry in human myometrial [PDF] [Full Text] [Abstract] 2007; 13 (3): 171-179*. Mol. Hum. Reprod. A. Dalrymple, K. Mahn, L. Poston, E. Songu-Mize and R.M. Tribe smooth muscle cells Mechanical stretch regulates TRPC expression and calcium entry in human myometrial [PDF] [Full Text] [Abstract] , October 1, 2008; 586 (19): 4631-4642. J Physiol Hollywood Gerard P. Sergeant, Eamonn Bradley, Keith D. Thornbury, Noel G. McHale and Mark A. interstitial cells of Cajal from the rabbit urethra waves in freshly dispersed 2+ Role of mitochondria in modulation of spontaneous Ca
منابع مشابه
Pacemaker activity in urethral interstitial cells is not dependent on capacitative calcium entry.
The aim of the present study was to investigate the properties and role of capacitative Ca(2+) entry (CCE) in interstitial cells (IC) isolated from the rabbit urethra. Ca(2+) entry in IC was larger in cells with depleted intracellular Ca(2+) stores compared with controls, consistent with influx via a CCE pathway. The nonselective Ca(2+) entry blockers Gd(3+) (10 microM), La(3+) (10 microM), and...
متن کاملOrigin of spontaneous rhythmicity in smooth muscle.
Rhythmic electrical activity is a feature of most smooth muscles but the mechanical consequences can vary from regular rapid phasic contractions to sustained contracture. For many years it was thought that spontaneous electrical activity originated in smooth muscle cells but recently it has become apparent that there are specialized pacemaker cells in many organs that are morphologically and fu...
متن کاملNovel excitatory effects of adenosine triphosphate on contractile and pacemaker activity in rabbit urethral smooth muscle.
PURPOSE Adenosine triphosphate is thought to be an important neurotransmitter in urethral smooth muscle but its physiological role is still unclear. We characterized the effects of adenosine triphosphate on contractile and pacemaker activity in rabbit urethral smooth muscle. MATERIALS AND METHODS Tension recordings were made from strips of rabbit proximal urethral smooth muscle. Membrane curr...
متن کاملRho-associated kinase plays a role in rabbit urethral smooth muscle
1 contraction, but not via enhanced myosin light chain phosphorylation 2 3 Michael P. WALSH, Keith THORNBURY, William C. COLE, Gerard SERGEANT, Mark 4 HOLLYWOOD and Noel McHALE 5 6 Smooth Muscle Research Group and Department of Biochemistry and Molecular Biology, Faculty of 7 Medicine, University of Calgary, Calgary, Alberta T2N 4N1, Canada, Smooth Muscle Research Centre, 8 Dundalk Institute of...
متن کاملThe effect of high [K+]o on spontaneous Ca2+ waves in freshly isolated interstitial cells of Cajal from the rabbit urethra
Interstitial cells of Cajal (ICC) act as putative pacemaker cells in the rabbit urethra. Pacemaker activity in ICC results from spontaneous global Ca(2+) waves that can be increased in frequency by raising external [K(+)]. The purpose of this study was to elucidate the mechanism of this response. Intracellular [Ca(2+)] was measured in fluo-4-loaded smooth muscle cells (SMCs) and ICC using a Nip...
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تاریخ انتشار 2005